Last updated on August 2019

Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial.


Brief description of study

In this double blind, randomized placebo controlled trial we aim to determine the efficacy of simvastatin as an add-on treatment for treatment resistant depression. We will recruit 150 people with treatment-resistant depression with the aim of determining whether the addition of simvastatin (20mg daily) to treatment as usual (TAU) for 12 weeks leads to an improvement in depressive symptom compared with placebo added to TAU.

Clinical Study Identifier: NCT03435744

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