Strategies for Hepatitis C Testing and Treatment in Aboriginal Communities That Lead to Elimination

  • End date
    Feb 25, 2022
  • participants needed
  • sponsor
    Kirby Institute
Updated on 25 January 2021
liver disease


A community-based "test and treat" intervention integrating point-of-care HCV RNA testing, non-invasive liver disease assessment and linkage to care will lead to a reduction in HCV prevalence among people attending Aboriginal health services.


SCALE-C is an interventional cohort study recruiting people with or at risk of HCV infection from Aboriginal health services in Australia. Participants will be screened for HCV infection using point-of-care testing (anti-HCV antibody and/or HCV RNA). People with current HCV infection (HCV RNA positive) will be offered treatment with eight or 12 weeks of pan-genotypic DAA therapy, glecaprevir/pibrentasvir or sofosbuvir/velpatasvir, as available on the PBS.

Condition Hepatitis A, LIVER DISEASE, Hepatitis, Hepatitis C, Hepatitis C virus, RNA Virus Infections, Hepatitis, Viral, Human, Viral infection, Digestive System Disease, Liver Disorders, Viral Infections, hepatic disease, hepatopathy, liver diseases, hepatic diseases, hepatic pathology, digestive disorders, digestive diseases, digestive disorder, digestive disease, acute hepatitis a, a hepatitis
Treatment Glecaprevir/Pibrentasvir, Fingerstick GeneXpert HCV RNA quantitative assay, sofosbuvir/velpatesvir
Clinical Study IdentifierNCT03776760
SponsorKirby Institute
Last Modified on25 January 2021


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Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Gender: Male or Female
Do you have any of these conditions: RNA Virus Infections or Viral infection or Viral Infections or Hepatitis A or LIVER DISEASE or Digestive System Disease or Hepatitis C virus or Liver ...?
Do you have any of these conditions: digestive diseases or a hepatitis or digestive disorder or Liver Disorders or LIVER DISEASE or Viral Infections or hepatopathy or Hepatitis or Viral i...?
years of age or older
voluntarily signed the informed consent form

Exclusion Criteria

Pregnant women
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