Food & You: A Healthy Diet Through Algorithms (FoodAndYou)

  • End date
    Dec 31, 2022
  • participants needed
  • sponsor
    Ecole Polytechnique Fédérale de Lausanne
Updated on 17 June 2022
Accepts healthy volunteers


Food & You is a large-scale citizen science research project in Switzerland. With this project, the researchers want to confirm that individuals respond differently to food, that is, that the blood sugar response (the level of sugar in the blood after a meal) varies among individuals, even after consumption of the same food or beverage. Secondly, the researchers want to develop an algorithm that will predict the individual blood sugar response and provide personalized diet recommendations.


Food & You is one of the first large-scale citizen science research project in Switzerland. This project is building on the results of Zeevi et al. study, which demonstrated in 2015 for the first time with a cohort of 800 participants that there is a high interpersonal variability in postprandial (postmeal) glycemic responses (PPGR). In a second stage, the group developed an algorithm that predicts PPGR and gives personalized diet recommendation to better control the blood sugar level. These results have only been shown once, if they turn out to be correct, it will have a very strong impact on the field of nutrition. Other studies have since then also shown the variability in glucose response, leading to the concept of individual "glucotypes". The most important particularity of Food & You is that it will be a citizen science project. Citizen science is a method that involves volunteers in scientific research activities. It increases scientific knowledge, raises people's awareness of scientific questions, and allows scientists to share enthusiasm and expertise. Furthermore, to enable any citizen to take part, the study will be entirely coordinated digitally. It means that unlike conventional studies, no face-to-face interviews or medical appointments will be organized. All instructions will be given by a website and emails / text messages sent to the participants. The study material will be sent by post and the data will be collected via the website and the MyFoodRepo app. The participants will have to track during 14 days:

  • Their dietary intake with the myFoodRepo app.
  • Their physical activity and sleep with a smartphone app or an activity tracker.
  • Their glucose level wearing the FreeStyle Libre Sensor.
  • Collect a stool sample. The microbiome composition will be analyzed by sequencing the 16s rDNA extracted from the stool sample.
  • Answer anthropometric, demographic, and health online questionnaires.

With the Food & You project, the research team will build a new algorithm that will predict PPGR with input that is readily available through such a "digital cohort" (i.e. low-burden on user, and affordable) in order to test whether this can scale to tens or hundreds of thousands of people. The results of this project may have substantial consequences in dietary guidelines, personalized diet and on health conditions related to dietary intake.

Condition Food Habits
Treatment Experimental: Single Arm
Clinical Study IdentifierNCT03848299
SponsorEcole Polytechnique Fédérale de Lausanne
Last Modified on17 June 2022


Yes No Not Sure

Inclusion Criteria

Men and women aged 18+
Have a postal address in Switzerland
Own a smartphone, minimum version iOS 10/Android 5
Sufficient knowledge of French, German or English to read and understand the instructions
Able to provide an informed consent

Exclusion Criteria

Persons on dialysis
Persons with chronic immunosuppressive medication usage
persons with skin disease, including contact dermatitis
Critically-ill patients
Usage of antibiotics in the three months prior to enrollment
Chronically active inflammatory or neoplastic disease in the three years prior to enrollment
Chronic gastrointestinal disorder, including Inflammatory Bowel Disease and Celiac disease
Active neuropsychiatric disorder
Myocardial infarction or cerebrovascular accident in the six months prior to enrollment
Pre-diagnosed type I or type II diabetes mellitus
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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