Efficiency of Neuromuscular Bite vs Physiotherapy in TMD Patients

  • sponsor
    University of L'Aquila
Updated on 22 January 2021
temporomandibular joint syndrome


Temporomandibular joint dysfunction (TMD) therapy remains an open challenge for modern dentistry. Usually physiotherapy is considered a reliable approach to treatment of TMD patients. Moreover, neuromuscular bites (orthotic) are able to reduce signs and symptoms of TMD. To our knowledge, no specific trials have been designed for the evaluation of the efficiency of physiotherapy vs neuromuscular bites in TMD patients.

The aim of this trial is to evaluate the efficiency in term of cranial muscles electromyography (sEMG), mandibular kinetic (KNG) and subjective pain scores, of orthotic vs manual physiotherapy therapy compared to placebo.

Condition TEMPOROMANDIBULAR JOINT DISORDER, Costen's Syndrome, transient myeloproliferative disorder, temporomandibular disorders, temporomandibular disorder, temporomandibular joint disorders, temporomandibular joint syndrome
Treatment Placebo, Neuromuscular Bite (orthotic), Mandibular Physiotherapy, Neuromuscular Bite (orthotic/sub-lingual)
Clinical Study IdentifierNCT02946645
SponsorUniversity of L'Aquila
Last Modified on22 January 2021


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Inclusion Criteria

Is your age between 25 yrs and 45 yrs?
Are you female?
Do you have any of these conditions: Costen's Syndrome or TEMPOROMANDIBULAR JOINT DISORDER?
Do you have any of these conditions: temporomandibular joint disorders or transient myeloproliferative disorder or TEMPOROMANDIBULAR JOINT DISORDER or Costen's Syndrome or temporomandibul...?
myogenous TMD
pain duration longer than 3 months
presence of complete permanent dentition, with the possible exception of the third molars
normal occlusion

Exclusion Criteria

Patients were excluded from the study if they met one or more of the following
presence of systemic or metabolic diseases
eye diseases or visual defects
history of local or general trauma
neurological or psychiatric disorders
muscular diseases
cervical pain
bruxism, as diagnosed by the presence of parafunctional facets and/or anamnesis of parafunctional tooth clenching and/or grinding
assumed use of anti-inflammatory, analgesic, anti-depressant, opioid, or myorelaxant -
fixed or removable prostheses
fixed restorations that affected the occlusal surfaces
and either previous or concurrent orthodontic or orthognathic treatment. For comparison with previous literature, the diagnosis of myofascial-type TMD was provided after clinical examination by a trained clinician according to group 1a and 1b of the Research Diagnostic Criteria for TMD (RDC/TMD), in a blinded manner
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