Last updated on July 2019

Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Exudative retinopathy
  • Age: - 16 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Coats disease confirmed by fundus examination and fluorescein angiography
  • Stage 2 or 3 at the fundus (Shields classification)
  • Naive to any eye treatment on the eye affected by Coats disease

Exclusion Criteria:

  • Other ocular pathology on the eye affected by Coats' disease
  • Bilateral forms of the disease
  • History of hypersensitivity to bevacizumab
  • History of hypersensitivity to products of Chinese hamster ovary cells or other recombinant human or humanized antibodies
  • Allergic reaction in a previous fluorescein retinal angiogram
  • Pregnancy or breastfeeding
  • Active or suspected periocular infection
  • Contraindication to treatments used for general anesthesia and morphine derivatives
  • Cardiovascular, haemorrhagic and gastrointestinal risks
  • Premature baby who has not reached the correct age of 37 weeks

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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