CLARITY 2 - Depression Research Study: Adjunctive Treatment of Major Depressive Disorder

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Updated on 12 January 2021


Summit Research Network is enrolling participants in an investigational medication research study for Major Depressive Disorder.  The purpose of this study is to  evaluate the efficacy and safety of adjunctive pimavanserin compared to placebo in subjects with major depressive disorder who have  inadequate response to antidepressant therapy. 

Qualified participants may be involved for up to 14 weeks and visit the research center 8 times.  At the first visit, qualified participants will enter a screening period. After the initial screening period participants will receive either the investigational medication or a placebo (an inactive substance) for up to 6 weeks and visit the research center weekly.  Thirty days after the last dose of theinvestigational medication, participants will complete a follow-up visit by phone.



Study-related psychological evaluation, physical exam, laboratory tests and ECG are provided to the research study participants at designated visits throughout the study. As with all studies at Summit, if you qualify for this research study all research related care, study medication and office visits will be provided at no cost.

Condition Depression, Depression (Major/Severe), Depression (Adolescent), Depression (Pediatric), Depression (Adult and Geriatric), Depression (Treatment-Resistant)
Clinical Study IdentifierTX224556
Last Modified on12 January 2021

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