Last updated on June 2019

A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF


Brief description of study

Idiopathic pulmonary fibrosis (IPF) is a rare, progressive life-threatening disease that is characterized by exertional dyspnea and persistent dry cough.

Cough in IPF is both a presenting and a complicating clinical feature, which affects approximately three quarters of IPF cases. It is often a debilitating symptom that adversely affects quality of life (QoL) and is usually refractory to medical therapy.

Inhaled RVT-1601 (formerly, PA101B), a new inhalation formulation of cromolyn sodium delivered via the eFlow Closed System (CS) nebulizer, is being evaluated in this Phase 2b study for the treatment of persistent cough in patients with IPF.

Clinical Study Identifier: NCT03864328

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University of Alabama

Birmingham, AL United States
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University of California Davis

Sacramento, CA United States
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University California San Francisco

San Francisco, CA United States
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National Jewish Health

Denver, CO United States
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University of Miami

Miami, FL United States
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Loyola University

Maywood, IL United States
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Tulane University

New Orleans, LA United States
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Universty of Michigan

Ann Arbor, MI United States
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University of Minnesota

Minneapolis, MN United States
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Mayo Clinic - Rochester

Rochester, MN United States
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St. Luke's Hospital

Chesterfield, MO United States
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American Health Research

Charlotte, NC United States
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Duke University

Durham, NC United States
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Cleveland Clinic

Cleveland, OH United States
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Spartanburg Medical Research

Spartanburg, SC United States
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University of Virginia

Charlottesville, VA United States
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INOVA Fairfax Hospital

Falls Church, VA United States
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VU Medical Center

Amsterdam, Netherlands
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St. Antonius Ziekenhuis

Nieuwegein, Netherlands
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Erasmus Medical Center

Rotterdam, Netherlands
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Recruitment Status: Open


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