Last updated on June 2019

Screening for Cardiac Amyloidosis Using Nuclear Imaging for Minority Populations

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Transthyretin-Related | Amyloid Cardiomyopathy
  • Age: Between 60 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Black or Hispanic of Caribbean origin.
  2. Age 60 years.
  3. Diagnosis of heart failure, confirmed by one of two methods:
  4. Modified criteria utilized by Rich et al. which include a history of acute pulmonary edema or the occurrence of at least two of the following that improved with diuretic therapy without another identifiable cause: dyspnea on exertion, paroxysmal nocturnal dyspnea, orthopnea, bilateral lower extremity edema or exertional fatigue, and
  5. National Health and Nutrition Examination Survey (NHANES) congestive heart failure (CHF) criteria with a score 3.
  6. Able to understand and sign the informed consent document after the nature of the study has been fully explained.

Exclusion Criteria:

  1. Primary amyloidosis (AL) or secondary amyloidosis (AA).
  2. Prior liver or heart transplantation.
  3. Active malignancy or non-amyloid disease with expected survival of less than 1 year.
  4. Heart failure, in the opinion of the investigator, primarily caused by either valve disease or ischemic heart disease.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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