Last updated on June 2019

Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition


Brief description of study

Patients with chronic kidney disease, who have evidence of systemic inflammation with increased cardiovascular risk, will be enrolled into this trial. The purpose of this trial is to determine a dose to select for a potential cardiovascular outcome trial with Ziltivekimab. Doses to be tested will be 7.5 mg, 15 mg and 30 mg subcutaneous monthly compared to placebo for six months.

Clinical Study Identifier: NCT03926117

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Central Alabama Research

Birmingham, AL United States
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Aventiv Research

Mesa, AZ United States
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Elite Clinical Studies

Phoenix, AZ United States
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Apex Research of Riverside

Riverside, CA United States
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AMPM Research Clinic

Miami, FL United States
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University of Iowa

Iowa City, IA United States
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Capital Nephrology

Greenbelt, MD United States
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Onyx Clinical Research

Caro, MI United States
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Henry Ford Health System

Detroit, MI United States
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St. Clair Nephrology Research

Roseville, MI United States
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Nephrology Research of Michigan

Saint Clair Shores, MI United States
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DaVita Clinical Research

Minneapolis, MN United States
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DaVita Clinical Research

Bronx, NY United States
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Northport VAMC

Northport, NY United States
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Rhode Island Hospital

Providence, RI United States
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Knoxville Kidney Center, PLLC

Knoxville, TN United States
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Nephrology Associates, PC

Nashville, TN United States
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Vilo Research Group, Inc

Houston, TX United States
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North Hills Medical Research, Inc

North Richland Hills, TX United States
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Clinical Advancement Center, PLLC

San Antonio, TX United States
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University of Vermont

Burlington, VT United States
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Recruitment Status: Open


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