Last updated on June 2019

2a Study to Assess the Efficacy and Safety of REGN3500 Monotherapy and Combination of REGN3500 Plus Dupilumab in Adult Patients With Moderate-to-Severe Atopic Dermatitis


Brief description of study

The primary objective of the study is to evaluate the efficacy of REGN3500 monotherapy compared with placebo treatment in adult patients with moderate-to-severe Atopic dermatitis (AD).

Secondary Objectives are to:

  • Evaluate the efficacy of REGN3500 in combination with dupilumab compared with placebo treatment in adult patients with moderate-to-severe AD
  • Assess the safety, tolerability, and immunogenicity of subcutaneous (SC) doses of REGN3500 monotherapy and REGN3500 in combination with dupilumab in adult patients with moderate-to-severe AD
  • Evaluate the Pharmacokinetic (PK) of REGN3500 monotherapy and REGN3500 in combination with dupilumab in adult patients with moderate-to-severe AD

Clinical Study Identifier: NCT03736967

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Regeneron Research Site

Fountain Valley, CA United States
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Long Beach, CA United States
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Los Angeles, CA United States
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Sacramento, CA United States
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Davie, FL United States
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Sandy Springs, GA United States
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Rockville, MD United States
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Bay City, MI United States
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Saint Joseph, MI United States
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Forest Hills, NY United States
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Regeneron Research Site

New York, NY United States
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High Point, NC United States
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Norman, OK United States
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Regeneron Research Site

Pittsburgh, PA United States
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Recruitment Status: Open


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