Electroacupuncture for Patients With Chronic Urinary Retention Secondary to Lower Motor Neuron Lesion

  • STATUS
    Recruiting
  • End date
    Dec 28, 2022
  • participants needed
    200
  • sponsor
    Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Updated on 28 November 2021

Summary

Chronic Urinary Retention (CUR) is defined as a non-painful bladder which remains palpable or percussible after the patient has passed urine by International Continence Society. Postvoid residual urine volume 300 mL seems to be widely accepted.

CUR may be caused by a variety of diseases and events including injury of sacral plexus, cauda equina and sacral spinal cord, pelvic floor nerve lesion after pelvic surgery and peripheral neuropathy due to diabetes, etc.. Aforementioned injuries generally affect lower motor neuron causing detrusor underactivity, acontractile detrusor or detrusor areflexia. The prevalence varies by different causes of lower motor neuron lesion. The symptoms of patients are voiding difficulty, bladder distention, bladder without sensation and overflow incontinence.

A multi-center randomized sham-controlled trial will be conducted. The aim of this study is to assess the efficacy and safety of electroacupuncture for urinary function of patients with CUR caused by lower motor neuron lesion.

Details
Condition Chronic Urinary Retention
Treatment Electroacupuncture, Sham electroacupuncture
Clinical Study IdentifierNCT03662906
SponsorGuang'anmen Hospital of China Academy of Chinese Medical Sciences
Last Modified on28 November 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Have chronic urinary retention caused by lower motor neuron damage
Age 18 to 75 years
Have chronic urinary retention caused by injury of sacral plexus, cauda equina and sacral spinal cord, pelvic floor nerve lesion after pelvic surgery and peripheral neuropathy due to diabetes
Have postvoid residual urine volume 300 mL or more and sensation of bladder
Bladder contractile index is more than 100 or more
Duration of disease is more than 3 months
Intermittent clean catheterization or indwelling catheterization
Sign informed consent and participate in the study voluntarily

Exclusion Criteria

Have urinary retention due to bladder outlet obstruction (bladder neck contracture, urethral stricture, prostate cancer, prostatic hyperplasia, etc.)
Have urinary system tumors or stones
Have detrusor underactivity due to other non-lower motor neurogenic disease
Have bowel and urinary disorder due to lesions or injuries of thoracic spinal cord, cervical spinal cord and brain
After suprapubic cystostomy
Have heart, liver, kidney, mental disorders or coagulation disorders
Have been implanted a cardiac pacemaker, sacral nerve stimulation electrode, pudendal nerve stimulation electrode, or bladder stimulation electrode
During pregnancy or in lactation
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note