Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms

  • End date
    Dec 31, 2030
  • participants needed
  • sponsor
    Francesco De Cobelli
Updated on 24 March 2022
radiofrequency ablation
primary liver cancer
kidney tumor
renal neoplasm
von hippel-lindau syndrome


Observational, retrospective and prospective, monocentric study. The objective is to evaluate the short, medium and long-term clinical course of patients undergoing microwave ablation (MWA) for small renal tumors and primary and secondary liver neoplasms. Evaluation of clinical efficacy (progression free survival),safety and technical outcome of microwave ablation as well as clinical outcome of the procedure will be evaluated.At the end of the follow-up periods, the data collected will be compared with those available in the literature on MWA, cryoablation (CA), radiofrequency ablation (RFA) and surgical resection.

Condition Liver Cancer, Liver Metastasis Colon Cancer, Kidney Cancer, Renal Cell Carcinoma
Treatment Microwave Ablation (MWA)
Clinical Study IdentifierNCT03981497
SponsorFrancesco De Cobelli
Last Modified on24 March 2022


Yes No Not Sure

Inclusion Criteria

> 18 years with primary or secondary liver tumors or small kidney tumors that are not candidates for surgery or cannot be radically resected by surgery alone
Primary liver cancer: up to three liver nodules ≤ 3 cm
Secondary hepatic tumours: up to nodules ≤ 3 cm provided that the objective is complete hepatic clearance Renal tumours: single or multiple (von Hippel Lindau syndrome), < 4 cm

Exclusion Criteria

pregnant women
non-manageable coagulopathies
Extended extrahepatic or extrarenal disease
for liver ablation: presence of bilio-digestive anastomosis
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