Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

  • STATUS
    Recruiting
  • End date
    May 17, 2023
  • participants needed
    412
  • sponsor
    Kymab Limited
Updated on 17 May 2022
cancer
monoclonal antibodies
measurable disease
carcinoma
breast cancer
squamous cell carcinoma
lung cancer
pd-l1
programmed cell death 1 ligand 1
solid tumour
triple negative breast cancer
solid neoplasm
squamous cell carcinoma of head and neck
atezolizumab
lung carcinoma

Summary

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their disease, or they have exhausted all such available options in each indication and therefore will be patients for whom a clinical trial is appropriate.

Details
Condition Squamous Cell Carcinoma of Head and Neck, Non-small Cell Lung Cancer, Hepatocellular Carcinoma, Esophageal Cancer, Gastric Cancer, Melanoma, Renal Cell Carcinoma, Pancreatic Cancer, Cervical Cancer, Triple Negative Breast Cancer, Advanced Cancer, Metastatic Cancer
Treatment KY1044, KY1044 and atezolizumab
Clinical Study IdentifierNCT03829501
SponsorKymab Limited
Last Modified on17 May 2022

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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