Clinical and Biological Database in Colon Cancer and Colic Tumors

  • STATUS
    Recruiting
  • End date
    Dec 25, 2030
  • participants needed
    600
  • sponsor
    Institut du Cancer de Montpellier - Val d'Aurelle
Updated on 25 January 2021

Summary

Developement of a clinical and biological database in colon cancer and colic tumors in order to better understand tumor invasion and metastatic scattering processes. The investigators hope that a better understanding of tumoral invasion process will lead to the discovery of new biomarkers and new drugs.

Description

As the second leading cause of cancer-related death in France, colorectal cancer is a major public health problem. Each year, 37 000 cases are newly diagnosed in France and 17 000 patients die of the disease.

Colorectal cancer is due to molecular and genetic damages involved in all tumorigenesis steps, transition from healthy tissue to adenoma and finally to invasive carcinoma stage. The investigators hope that a to better understand tumor invasion and metastatic scattering processes will allow therapeutic innovation and the emergence of new biomarkers.

However, the study of early tumorigenesis phases as well as advanced stages of the disease is currently limited due to a lack of tissue samples.

In this context, the Montpellier Cancer Institute (ICM) decided to initiate a biological collection dedicated to the tissular and blood samples of patients with colorectal cancer.

Details
Condition Malignant neoplasm of colon, Colon Cancer
Treatment Biological collection
Clinical Study IdentifierNCT03976960
SponsorInstitut du Cancer de Montpellier - Val d'Aurelle
Last Modified on25 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patient undergoing colon cancer surgery (stage I, II, III and IV)
Patient operated for liver or lung or peritoneal carcinomatosis metastases originating from colon cancer
Patient operated for pre-neoplastic lesion (adenomatous polyp /villous adenoma polyp)
Patient with familial polyposis eligible for colectomy
Age > 18 years
Signed informed consent

Exclusion Criteria

Patient not affiliated to Social Protection system
Patient unable to understand or comply with study instructions or requirements for psychological, family, social or geographical reasons
Patient under guardianship
Minor patient
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