Regional Anesthesia for Breast Surgery

  • STATUS
    Recruiting
  • End date
    Jun 23, 2022
  • participants needed
    150
  • sponsor
    Arcispedale Santa Maria Nuova-IRCCS
Updated on 23 January 2021
breast surgery
mastectomy

Summary

Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block. In both groups, blocks will be performed with 20 ml of ropivacaine 0.75%, plus ropivacaine 0.375% 10 ml for parasternal block only.

Postoperative, all patients will receive a morphine PCA. They will follow at 6, 12, 24 months for persistent postoperative surgical pain (PPSP) and cancer recurrence.

Description

Patients scheduled for mastecotmy with or without axillary dissection, will be randomized to receive preoperative either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block. In both groups, blocks will be performed with 20 ml of ropivacaine 0.75%, plus ropivacaine 0.375% 10 ml for parasternal block only.

All the patients also received a general anesthesia induced by propofol and esmeron for endotracheal intubation and desflurane for maintaining.

Sensory block by ice and pinprick test application and maximum spread after 40' from LA injection will be registered.

Postoperative, all patients will receive a morphine PCA, ketorolac 30 mg/12h and paracetamol 1g each 8h.

Morphine consumption will be registered. Patients will follow at 6, 12, 24 months for persistent postoperative surgical pain (PPSP) and cancer recurrence.

Details
Condition Breast Cancer, Breast Cancer Diagnosis, breast carcinoma, cancer, breast
Treatment PECSII and paravertebral blocks
Clinical Study IdentifierNCT03941223
SponsorArcispedale Santa Maria Nuova-IRCCS
Last Modified on23 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Are you female?
Do you have Breast Cancer?
Do you have any of these conditions: Breast Cancer Diagnosis or cancer, breast or Breast Cancer or breast carcinoma?
Patients scheduled for radical mastectomy for cancer
age > 18 y-o
Written informed consent

Exclusion Criteria

Bilateral surgery
Opioids user
BMI > 35
Postoperative Intensive care
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