Last updated on June 2019

FMT in Inflammatory Bowel Disease

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Microscopic colitis | Faecal Microbiota Transplantation | Crohn's Disease | Ulcerative Colitis
  • Age: Between 18 - 65 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Patients with inflammatory bowel disease (Crohn's disease or Ulcerative colitis) or Microscopic Colitis proven on the basis of radiology, endoscopy or histology.
  • Patients with clinically and endoscopically active, Crohn's Disease, Ulcerative Colitis or Microscopic Colitis
  • Patient must have attempted reasonable medical therapies to control their disease without sufficient response.
  • All patients have to be capable of attending appointments, as well completing surveys and diagnostic tests for the duration of study follow up
  • The patient must be able to identify a likely stool donor

Exclusion Criteria:

  • Patients with an enteropathy or colitis which cannot definitively be diagnosed as Ulcerative Colitis, Crohn's disease or Microscopic colitis
  • Patients with concurrent Clostridium difficile infection
  • Women who are pregnant or intending to become pregnant in the near future (less than 6 months).
  • Neutrophils less than 1.0 x 109/L
  • Albumin less than 20g/L
  • Active gastrointestinal infection as identified by testing
  • A patient on steroids (prednisolone, budesonide) at a dose that cannot be safely tapered to zero within 6 weeks of initial FMT, due to the risk of adrenal insufficiency
  • Short gut syndrome and/or small intestine less than 1.5m in length as measured intra-operatively
  • Perforation or active internal fistulising disease or enterocutaneous fistulae.
  • Any patient that the clinicians feel is incapable of participating in the safe use of FMT.
  • Current use of antibiotics for any condition

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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