Last updated on July 2020

An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Patients Who Participated in Prior Roche and Genentech Sponsored Studies

Brief description of study

This study will evaluate the long-term safety and tolerability of RO7234292 (RG6042) in participants who have completed other F. Hoffmann-La Roche, Ltd.-sponsored and/or Genentech-sponsored studies in the Huntington's disease (HD) in the development program for RG6042.

Detailed Study Description

Entry into the study should occur at the time the participant completes participation in one of the preceding studies. Upon completion of the inclusion visit, eligible patients will receive either RO7234292 (RG6042) every 8 weeks (Q8W) or RO7234292 (RG6042) every 16 weeks (Q16W) by bolus intrathecal injection.

Clinical Study Identifier: NCT03842969

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Uab Medicine

Birmingham, AL United States
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Stanford Univ Medical Center

Palo Alto, CA United States
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SC3 Research Group, Inc

Pasadena, CA United States
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Columbia University

New York, NY United States
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University of Pittsburgh

Pittsburgh, PA United States
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Northwestern University

Chicago, IL United States
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Dent Neurological Institute

Amherst, NY United States
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Leiden, Netherlands
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Recruitment Status: Open

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