Last updated on January 2020

Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Pelvic Floor Disorders | Stress incontinence
  • Age: Between 21 - 100 Years
  • Gender: Female

Inclusion Criteria:

  • At least 21 years of age
  • Women being considered for a native tissue vaginal repair in any vaginal compartment or colpocleisis
  • POP stage II of any vaginal compartment, according to the pelvic organ prolapse quantification (POP-Q) system
  • Vaginal bulge symptoms
  • Positive standardized cough stress test on clinical examination, or on urodynamic testing
  • Surgical plan that includes a native tissue vaginal repair including colpocleisis for symptomatic POP in any compartment
  • Understanding and acceptance of the need to return for all scheduled follow-up visits
  • English speaking and able to give informed consent
  • Willing and able to complete all study questionnaires

Exclusion Criteria:

  • Prior surgery for stress urinary incontinence
  • Status post reconstructive pelvic surgery with transvaginal mesh kits or sacrocolpopexy with synthetic mesh for prolapse
  • Any serious disease, or chronic condition, that could interfere with the study compliance
  • Unwilling to have a synthetic sling
  • Inability to give informed consent
  • Pregnancy or planning pregnancy in the first postoperative year
  • Untreated urinary tract infection (may be included after resolution)
  • Poorly-controlled diabetes mellitus (HgbA1c > 9 within 3 months of surgery date)
  • Prior pelvic radiation
  • Incarcerated
  • Neurogenic bladder/ pre-operative self-catheterization
  • Elevated post-void residual (>150 ml) that does not resolve with prolapse reduction testing (pessary, prolapse reduced uroflow or micturition study)
  • Prior augmented (synthetic mesh, autologous graft, xenograft, allograft) prolapse repair
  • Planned concomitant bowel related surgery including sphincteroplasty and perineal rectal prolapse surgery, rectovaginal fistula repair, hemorrhoidectomy.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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