Immunological Follow-up After Allogeneic Hematopoietic Stem Cell Transplantation (SIA-CSH)

  • End date
    May 31, 2029
  • participants needed
  • sponsor
    Institut Paoli-Calmettes
Updated on 9 February 2022


Description of the evolution of the biological characteristics of immune blood populations and biomarkers of interest in patients who have received allogeneic hematopoietic stem cell transplantation.


a more in-depth analysis of the different immune cell sub-populations as well as serum markers (cytokines) would provide a better understanding of post-allograft immune reconstitution mechanisms and identify potential immunologic biomarkers predictive of GVH or relapse.

Condition Malignant Hemopathy
Treatment Blood samples (additional tubes from care) longitudinal, Blood samples (additional tubes from care) at inclusion
Clinical Study IdentifierNCT03965429
SponsorInstitut Paoli-Calmettes
Last Modified on9 February 2022


Yes No Not Sure

Inclusion Criteria

Allogeneic hematopoietic stem cell transplant for hematological malignancy
Patients 18 years of age or older
Signed consent to participation
Membership in a social security scheme, or beneficiary of such a scheme

Exclusion Criteria

A person of legal age subject to a legal protection measure (major under guardianship, curatorship or court bail), or unable to express consent (language criteria included)
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