The Individual Therapy for Patients With Wilson's Disease

  • STATUS
    Recruiting
  • End date
    Dec 31, 2024
  • participants needed
    400
  • sponsor
    Second Affiliated Hospital, School of Medicine, Zhejiang University
Updated on 9 February 2022
zinc
dmsa
penicillamine
dmps

Summary

Based on the genotype characteristics and genotype-phenotype-treatment prognosis data of Chinese WD patients, this study intends to further optimize the treatment regimen of Chinese WD patients and formulate individualized treatment regimens for each genotype, so as to further improve the prognosis of patients.

Description

The purpose of the study is to evaluate treatment regimen efficacy based on different mutations, and Zinc treatment in presymptomatic WD patients.

Details
Condition Wilson's Disease
Treatment Zinc gluconate, Penicillamine, DMSA, DMPS, DMPS
Clinical Study IdentifierNCT03957720
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
Last Modified on9 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Genetic diagnosis of Wilson's disease
Presymptomatic patients with Wilson's disease

Exclusion Criteria

Movement disorder due to other definite causes instead of Wilson's disease
Severe Lung, kidney or liver disease
Neoplastic Disease
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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