Pulmonary Hemodynamics During Exercise - Research Network

  • STATUS
    Recruiting
  • End date
    Dec 31, 2023
  • participants needed
    1500
  • sponsor
    Medical University of Graz
Updated on 24 September 2020
Investigator
Gabor Kovacs, MD
Primary Contact
Royal Prince Alfred Hospital, Respiratory Medicine (7.6 mi away) Contact
+39 other location

Summary

The purpose of this Clinical Research Collaboration is to investigate the prognostic implications of pulmonary hemodynamics during exercise based on a large scale multi-centre approach by using retrospective and prospective analysis of hemodynamic data.

Details
Treatment assessment of pulmonary hemodynamics during exercise by right heart catheterization
Clinical Study IdentifierNCT03954574
SponsorMedical University of Graz
Last Modified on24 September 2020

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Eligibility

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Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Gender: Male or Female
Do you have Pulmonary Circulation Diseases?
Patients (females and males; age: above 18yrs) with intermediate or high echocardiographic probability of PH and/or unexplained dyspnea, and/or associated conditions for PAH as clinical indication for RHC at rest and exercise
Written informed consent of participating subjects after being fully briefed (for prospective analysis)

Exclusion Criteria

Patients with incomplete hemodynamic data at rest or exercise
Patients without sufficient follow-up data (information on survival / lung transplantation)
advanced tumour disease or other diseases with a short life expectancy, except pulmonary vascular diseases
advanced heart failure with pulmonary arterial wedge pressure (PAWP) > 18 mmHg at rest
uncontrolled systemic arterial hypertension (RR values > 160/100 mmHg at rest)
FEV1<50% predicted
TLC<60% predicted
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