Last updated on May 2019

Vitamin C to Reduce Vasopressor Dose in Septic Shock


Brief description of study

Randomized, controlled, double blind clinical trial. Adult patients admitted to the ICU of the Hospital Espaol de Mxico with a diagnosis of septic shock will be included.

Patients will be randomized to one of the study groups:

Intervention Group: Vitamin C 6 grams in 250 ml of 0.9% saline solution every 24 hours, in continuous infusion for 72 hours.

Placebo Group: 0.9% saline solution 250 ml every 24 hours, in continuous infusion for 72 hours.

Detailed Study Description

Randomized, controlled, double blind clinical trial. Adult patients admitted to the ICU of the Hospital Espaol de Mxico with a diagnosis of septic shock will be included.

Patients will be randomized to one of the study groups:

Intervention Group: Vitamin C 6 grams in 250 ml of 0.9% saline solution every 24 hours, in continuous infusion for 72 hours.

Placebo Group: 0.9% saline solution 250 ml every 24 hours, in continuous infusion for 72 hours.

Bottles will be identical, only identified by the sequential number of the patient that has been included.

Primary objective is to demonstrate that the administration of intravenous Vitamin C decreases the dose of exogenous vasopressors in patients with septic shock

Clinical Study Identifier: NCT03835286

Find a site near you

Start Over

Hospital Espa ol

Mexico City, Mexico
  Connect »