Last updated on May 2019

Ovarian Platelet Rich Plasma Treatment for Poor Responders

Brief description of study

Autologous ovarian Platelet Rich Plasma (PRP) treatment may enable ovarian rejuvenation, increase of AMH levels, and improved oocyte retrieval yield in poor responders undergoing single IVF cycle.

Detailed Study Description

The specific prospective clinical investigation, aims to answer whether autologous Platelet reactivation of the ovarian tissue functionality.

PRP is blood plasma prepared from fresh whole blood that has been enriched with platelets. It is collected from peripheral veins and contains several growth factors such as vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), platelet derived growth factor (PDGF), transforming growth factor (TGF) and other cytokines all of which stimulate tissue proliferation and growth. PRP has been employed in several medical conditions in Orthopedics, Dermatology, Ophthalmology for wound healing. It's efficacy in ovarian rejuvenation and reactivation and endometrial regeneration has not been fully elucidated.

The aim of this study is to evaluate the effectiveness of ovarian PRP injection, in order to reactivate ovarian function.

Clinical Study Identifier: NCT03937661

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Genesis AC

Athens, Greece
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Recruitment Status: Open

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