Last updated on September 2020

Copeptin After an Oral Stimulation With Macimorelin in Healthy Volunteers

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Polyuria-polydipsia Syndrome
  • Age: Between 18 - 60 Years
  • Gender: Male or Female

Inclusion Criteria:

  • No medication except hormonal contraception

Exclusion Criteria:

  • Body Mass Index (BMI) > 40kg/m2 or BMI < 18.5 kg/m2
  • participation in a trial with investigational drugs within 30 days
  • vigorous physical exercise within 24 hours before the study participation
  • Alcohol intake within 24 hours before study participation
  • pregnancy and breastfeeding
  • Evidence of disordered drinking habits and diuresis defined as polyuria >50ml/kg body weight/24h and polydipsia >3l /24h
  • a prolonged QT interval (QTc >500 ms) or concomitant treatment with drugs that prolong the QT/QTc.
  • Intention to become pregnant during the course of the study
  • Known allergy towards Macimorelin

Recruitment Status: Closed

Brief Description Eligibility Contact Research Team

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