Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

  • End date
    Jul 1, 2026
  • participants needed
  • sponsor
    University of Wisconsin, Madison
Updated on 3 March 2021
breast cancer
squamous cell carcinoma
carcinoma in situ
ductal carcinoma in situ
breast-conserving surgery
invasive carcinoma
partial breast irradiation
breast irradiation


This trial will investigate a novel 3-fraction radiation regimen for participants undergoing breast-conserving therapy (BCT) for early breast cancer that will: 1) significantly reduce the duration of treatment and can be completed in one-week (5 working days) and 2) MRI-guided radiotherapy (MRIdian) would limit the volume of normal tissue radiated and therefore resultant toxicity. The hypothesis is that 3-fraction radiation therapy can be delivered safely without compromising the therapeutic ratio. Participants can expect to be on study for follow up up to 5 years.

Condition Ductal Carcinoma In Situ, Adenocarcinoma, Breast Cancer, Breast Cancer Diagnosis, Ductal Carcinoma In Situ (DCIS), Lobular Carcinoma In Situ, Malignant Adenoma, LCIS, breast carcinoma, cancer, breast, dcis
Treatment MRIdian Radiation Treatment Unit
Clinical Study IdentifierNCT03936478
SponsorUniversity of Wisconsin, Madison
Last Modified on3 March 2021

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note