Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

  • STATUS
    Recruiting
  • End date
    Jul 1, 2026
  • participants needed
    30
  • sponsor
    University of Wisconsin, Madison
Updated on 3 March 2021
cancer
carcinoma
breast cancer
squamous cell carcinoma
carcinoma in situ
lumpectomy
ductal carcinoma in situ
breast-conserving surgery
mammogram
invasive carcinoma
partial breast irradiation
breast irradiation

Summary

This trial will investigate a novel 3-fraction radiation regimen for participants undergoing breast-conserving therapy (BCT) for early breast cancer that will: 1) significantly reduce the duration of treatment and can be completed in one-week (5 working days) and 2) MRI-guided radiotherapy (MRIdian) would limit the volume of normal tissue radiated and therefore resultant toxicity. The hypothesis is that 3-fraction radiation therapy can be delivered safely without compromising the therapeutic ratio. Participants can expect to be on study for follow up up to 5 years.

Details
Condition Ductal Carcinoma In Situ, Adenocarcinoma, Breast Cancer, Breast Cancer Diagnosis, Ductal Carcinoma In Situ (DCIS), Lobular Carcinoma In Situ, Malignant Adenoma, LCIS, breast carcinoma, cancer, breast, dcis
Treatment MRIdian Radiation Treatment Unit
Clinical Study IdentifierNCT03936478
SponsorUniversity of Wisconsin, Madison
Last Modified on3 March 2021

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