Blood Flow Restriction Following ACL Reconstruction

  • STATUS
    Recruiting
  • End date
    Nov 1, 2022
  • participants needed
    60
  • sponsor
    Inova Health Care Services
Updated on 1 August 2021

Summary

The main objective is to determine the impact of Blood Flow Restriction (BFR) therapy, in comparison to a standard rehabilitation protocol, on preventing atrophy, improving quadriceps strength and improving functional outcomes of patients recovering from ACL reconstruction. The investigators hypothesize that patients undergoing BFR therapy after ACL reconstruction surgery will have better functional outcomes than those undergoing normal rehabilitation without BFR therapy.

Description

Recovery from anterior cruciate ligament (ACL) reconstruction involves early physical therapy to promote muscular development. Traditional training regimens are based on the concept that muscle growth is induced with high resistance exercises of at least 65-70% of 1-repetition maximum. Achieving a high resistance level can be challenging in the early post-surgical patient who may be limited by pain, muscle atrophy, diminished proprioception, and psychological factors. Increasing evidence has suggested that Blood Flow Restriction (BFR) in resistance training, while transmitting a decreased load (25-50% of 1-repetition maximum) across the surgical site, may provide an additional benefit of inducing muscular development similar to that of high intensity exercises .

Augmenting exercises with BFR involves an external pressure cuff applied to the proximal portion of the extremity, which is inflated to a pressure that restricts venous outflow while allowing arterial inflow to continue. This creates a physiologic environment for the patient to gain the hypertrophic effect of high resistance training, though at a lower and safer intensity. Studies suggest that BFR stimulates muscular development through an increase in metabolic stress, muscle fiber recruitment, cell swelling, and protein synthesis.

Details
Condition Anterior Cruciate Ligament Tear, Rupture of Anterior Cruciate Ligament, Anterior Cruciate Ligament Rupture
Treatment Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
Clinical Study IdentifierNCT03758755
SponsorInova Health Care Services
Last Modified on1 August 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Age 13-35 years at the time of surgery
ACL reconstruction
Using a physical therapy center with Blood Flow Restriction capabilities

Exclusion Criteria

Concomitant ligament reconstruction
Concurrent procedures that require delayed weight bearing (ie: HTO, multiligament reconstruction, microfracture, etc)
History of DVT/PE
Immunocompromising conditions (ie: Rheumatoid arthritis, chronic steroid use, etc.)
History of coagulation disorders or current use of anticoagulants
Completion of physical therapy at a location not affiliated with the study
Pregnancy
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