Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

  • End date
    Sep 1, 2022
  • participants needed
  • sponsor
    New York State Psychiatric Institute
Updated on 30 April 2021
opioid use
drug abuse
cannabis use
narcotic use
pain relieving
prescription drugs


The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-liability effects of a sub-threshold dose of a commonly used analgesic.

Condition Drug abuse, Pain, Acute Pain Service, Post-Surgical Pain, Pain (Pediatric), Substance Abuse, Drug use, ache
Treatment Placebo, Oxycodone, Cannabis (THC:CBD = ~ 1:0), Cannabis (THC:CBD = ~ 0:1), Cannabis (THC:CBD = ~ 1:1)
Clinical Study IdentifierNCT03679949
SponsorNew York State Psychiatric Institute
Last Modified on30 April 2021


Yes No Not Sure

Inclusion Criteria

Male or non-pregnant female aged 21-53 years
Previous cannabis use
Previous opioid use
Urine test positive for recent cannabis use
Being able to perform all study procedures
Currently practicing an effective form of birth control (women only)

Exclusion Criteria

Meeting criteria for some Use Disorders
Report regular illicit drug use
If medical history, physical and psychiatric examination, or laboratory tests performed during the screening process revealed any significant illness
Clear my responses

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