Characterization of the Microbiome in Cutaneous T Cell Lymphoma

  • End date
    Dec 31, 2023
  • participants needed
  • sponsor
    Northwestern University
Updated on 6 February 2022
skin disorder
lymphoproliferative disorder
anaplastic large cell lymphoma
large cell lymphoma
Accepts healthy volunteers


Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.

Condition Cutaneous T Cell Lymphoma
Clinical Study IdentifierNCT03932279
SponsorNorthwestern University
Last Modified on6 February 2022


Yes No Not Sure

Inclusion Criteria

Group 1: Patients with stage IA-IIA cutaneous T cell lymphoma
Group 2: Patients with stage IIB and above cutaneous T cell lymphoma
Group 3: Patients with CD30+ lymphoproliferative disorder including lymphomatoid papulosis and cutaneous anaplastic large cell lymphoma
Group 4: Patients with plaque psoriasis with BSA>5% on routine phototherapy per standard of care
Group 5: Patients with moderate to severe atopic dermatitis on routine bleach bath therapy per standard of care
Group 6: Healthy individuals without the above skin conditions, similar age and sex distribution to the patients with cutaneous T cell lymphoma
All Groups: subjects who are age 18-89 years of age at time of enrollment
All Groups: Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443)

Exclusion Criteria

All Groups: Subjects who are younger than 18 years of age or older than 90 years of age
All Groups: Subjects who are unable to give consent
Patients currently on systemic antibiotics or recent (within past 4 weeks) exposure to systemic antibiotics
We will not recruit the following populations: adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, prisoners and other vulnerable populations
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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