Last updated on February 2020

A Study of DCC-2618 vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib


Brief description of study

This is a 2-arm, randomized, open-label, international, multicenter study comparing the efficacy of DCC-2618 to sunitinib in GIST patients who progressed on or were intolerant to first-line anticancer treatment with imatinib. Approximately 358 patients will be randomized in a 1:1 ratio to DCC-2618 150 mg once daily (QD) (continuous dosing for 6 week cycles) or sunitinib 50 mg QD (6 week cycles, 4 weeks on, 2 weeks off).

Clinical Study Identifier: NCT03673501

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Mayo Clinic Florida

Jacksonville, FL United States
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Georgia Cancer Specialists

Sandy Springs, GA United States
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Mayo Clinic

Rochester, MN United States
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University of Toledo

Toledo, OH United States
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Fox Chase Cancer Center

Philadelphia, PA United States
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Emily Couric Clinical Cancer Center

Charlottesville, VA United States
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Stephenson Cancer Center

Oklahoma City, OK United States
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The Alfred Hospital

Melbourne, Australia
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Smilow Cancer Hospital at Yale

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Winship Cancer Institute

Atlanta, GA United States
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IU Simon Cancer Center

Indianapolis, IN United States
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The Monter Cancer Center

Lake Success, NY United States
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Stanford Medicine

Stanford, CA United States
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Sanatorio Allende

Córdoba, Argentina
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UZ Leuven

Leuven, Belgium
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IPC

Marseille, France
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Paris, France
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Asan Medical Center

Seoul, Korea, Republic of
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Samsung Medical Center

Seoul, Korea, Republic of
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Ajou University Hospital

Suwon, Korea, Republic of
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Sheffield, United Kingdom
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Córdoba, Argentina
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Mayo Clinic Scottsdale

Scottsdale, AZ United States
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Moffitt Cancer Center

Tampa, FL United States
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Baltimore, MD United States
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Henry Ford Health System

Detroit, MI United States
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Córdoba, Argentina
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Sanatorio Allende

Córdoba, Argentina
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Antoni van Leeuwenhoek

Amsterdam, Netherlands
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