A Single-Arm Study of Bempegaldesleukin (NKTR-214) Plus Nivolumab in Cisplatin Ineligible Patients Who Have Locally Advanced or Metastatic Urothelial Cancer

  • STATUS
    Not Recruiting
  • End date
    Jul 12, 2022
  • participants needed
    190
  • sponsor
    Nektar Therapeutics
Updated on 30 May 2021
Investigator
Nektar Recruitment
Primary Contact
Local Institution - Madrid (3.7 mi away) Contact
+255 other location
cancer
measurable disease
carcinoma
nivolumab
systemic chemotherapy
metastatic urothelial carcinoma

Summary

The main purpose of this study is to evaluate the anti-tumor activity of bempegaldesleukin (NKTR-214) in combination with nivolumab by assessing the objective response rate (ORR) in cisplatin ineligible, locally advanced or metastatic urothelial cancer patients.

Details
Condition urinary tract neoplasm, Metastasis, bladder cancer, bladder disorder, Liver Metastases, Bone Metastases, Brain Metastases, Urothelial Cancer, Metastatic Cancer, Bladder Disorders, Neoplasm Metastasis, Bladder Carcinoma, Urologic Cancer
Treatment Nivolumab, NKTR-214, Reference Gemcitabine, Reference Carboplatin, bempegaldesleukin
Clinical Study IdentifierNCT03785925
SponsorNektar Therapeutics
Last Modified on30 May 2021

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