A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel

  • End date
    Mar 31, 2022
  • participants needed
  • sponsor
    Bristol-Myers Squibb
Updated on 21 July 2021


The purpose of this clinical study is to determine whether the addition of an oral Factor XIa Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary stroke prevention.

Condition Transient Ischemic Attack, Acute Ischemic Stroke, transient ischemic attacks
Treatment Clopidogrel, Placebo, Aspirin, BMS-986177, BMS-986177 Placebo
Clinical Study IdentifierNCT03766581
SponsorBristol-Myers Squibb
Last Modified on21 July 2021


Yes No Not Sure

Inclusion Criteria

Male and Female 40 years of age
Acute Ischemic Stroke or Transient Ischemic Attack
Intracranial or Extracranial Atherosclerotic Plaque proximal to the affected brain area

Exclusion Criteria

Predicted inability to swallow study medication
Any condition that, in the opinion of the Investigator, contraindicates anticoagulant therapy or would have an unacceptable risk of bleeding
Use of thrombolytic therapy or mechanical thrombectomy for treatment of index stroke
Other protocol defined inclusion/exclusion criteria could apply
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