Tislelizumab in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Carcinoma

  • End date
    Aug 25, 2022
  • participants needed
  • sponsor
Updated on 11 August 2021


This is a randomized (1:1), double-blind, placebo-controlled, Phase 3 study designed to compare the efficacy and safety of tislelizumab or placebo plus chemotherapy as first-line (1L) therapy for locally advanced unresectable or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma.

Condition Gastric or Gastroesophageal Junction Adenocarcinoma
Treatment Capecitabine, cisplatin, Placebo, Oxaliplatin, 5-FU, tislelizumab, Tislelizumab (BGB-A317) combined with oxaliplatin and capecitabine or Tislelizumab (BGB-A317) combined with Cisplatin and 5-FU, Placebo combined with oxaliplatin and capecitabine or Placebo combined with Cisplatin and 5-FU
Clinical Study IdentifierNCT03777657
Last Modified on11 August 2021

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