Last updated on May 2020

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Autoimmune disease | IgA nephropathy | Glomerulonephritis
  • Age: Between 18 - 65 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Diagnosed with primary IgAN
  • Currently being treated for IgAN with stable, optimal therapy, including an ACE inhibitor or an ARB or a direct renin-inhibitor
  • Has urine protein greater than or equal to 1 gram/24-hour
  • Has hematuria (blood cells present in urine)

Exclusion Criteria:

  • Has renal disease other than IgAN
  • Has a diagnosis of rapidly progressive glomerulonephritis
  • Has a diagnosis of Henoch-Schonlein Purpura (IgA Vasculitis)
  • Has poor kidney function with estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m^2
  • Has known human immunodeficiency virus (HIV) infection, hepatitis C virus (HCV) infection or hepatitis B virus (HBV) infection
  • Has on-going high blood pressure
  • Treated with systemic corticosteroids for more than 7 days, or other immunosuppressant agents in the past 12 months
  • Received an organ transplant

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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