CAR-T Cell Therapy Targeting to CD19 for R/R ALL
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- STATUS
- Recruiting
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- End date
- Dec 31, 2023
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- participants needed
- 50
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- sponsor
- The First Affiliated Hospital of Soochow University
Summary
Refractory and relapsed (R/R) acute lymphoblastic leukemia (ALL) patients with active disease always have a dismal outcome. Chimeric antigen receptor (CAR) T-cell therapy targeting to Cluster of Differentiation Antigen 19 (CD19) has been proved as a potent approach to attain remission in B-cell R/R patients. Therefore, the investigators conduct a trial to evaluate the the efficacy and safety of locally producing CAR T cells targeting CD19, and to analyze the outcome of enrolled B-cell ALL patients with active disease or persistent residual disease.
Details
| Condition | Acute Lymphoblastic Leukemia With Failed Remission |
|---|---|
| Treatment | CAR T-cell therapy |
| Clinical Study Identifier | NCT03919240 |
| Sponsor | The First Affiliated Hospital of Soochow University |
| Last Modified on | 3 February 2022 |
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