Last updated on February 2020

A Phase I Study Comparing Pharmacokinetics and Safety of Bevacizumab


Brief description of study

The aim of the Clinical study is to evaluate the pharmacokinetic and safety profile of a new formulation of Bevacizumab (Zutrab) when compared to two already marketed formulations Avastin and Cizumab, to establish similarity.

Detailed Study Description

Three-way bridge phase 1 trial. It is conducted in healthy, male adult subjects, it is single-dose, double-blind, parallel groups, randomized and balanced.

Blood samples are collected up to 90 days, to dermine serum drug concentration and anti-drug antibodies. Safety and tolerabilty is also evaluated.

Clinical Study Identifier: NCT03919448

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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