Last updated on December 2019

A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil Oxaliplatin and Bevacizumab in Patients With Advanced Colorectal Cancer


Brief description of study

This is a multicenter, randomized, parallel-group, Phase III study in at least 440 patients with advanced colorectal cancer to compare the efficacy of treatment with arfolitixorin versus Leucovorin in combination with 5-fluorouracil, oxaliplatin, and bevacizumab according to modified FOLFOX-6 until PD according to RECIST 1.1 criteria.

Clinical Study Identifier: NCT03750786

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Georgetown University

Washington, WA United States
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Pinellas Hematology Oncology

Saint Petersburg, FL United States
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Cancer Center of Kansas

Wichita, KS United States
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S dersjukhuset

Stockholm, Sweden
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University of Southern California

Los Angeles, CA United States
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UCH-MHS d/b/a Memorial Health System

Colorado Springs, CO United States
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HOAG Memorial Hospital

Newport Beach, CA United States
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Krankenhaus Nordwest GmbH

Frankfurt am Main, Germany
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Wayne State University

Detroit, MI United States
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840-33 - Cedars-Sinai

Los Angeles, CA United States
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840-15 - HOAG Memorial Hospital

Newport Beach, CA United States
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840-23 - Georgetown University

Washington, WA United States
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840-08 - Pinellas Hematology Oncology

Saint Petersburg, FL United States
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840-36 - Clinical Oncology Associates

Farmington Hills, MI United States
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840-31 - Penn State Health

Hershey, PA United States
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Mount Sinai-Union Square

New York, NY United States
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