Adolescent Depression Associated With Parental Depression

  • End date
    Mar 28, 2023
  • participants needed
  • sponsor
    University Hospital, Brest
Updated on 3 February 2021
depressed mood


Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care.

In children the existence of a parental depression is a significant and recognized risk factor for the development of a depression. It is regularly reported that 30% of adolescents of depressed parents have depression themselves. General Practitioners (GP) have significant access to the depression of adults, potentially parents of teenagers. In fact, 20% of patients in the regular active file of one GP have depression. The primary health care system could provide indirect but voluminous and unprecedented access to the identification of adolescent depression at an early stage from the encounter of depressed parents.

The difficulties of articulation between primary care (PC) and mental health devices are demonstrated. They disrupt the care pathways of adolescents detected in PC, prevention, and may even disturb early detection of depression. An organized joint between the PC and a specialized mental health service for adolescents ("Maison Des Adolescents" MDA) could promote the process of screening and preventing depression of adolescents of depressed parents encountered in PC.

In addition, if the effects of parental depression on adolescents are established, they remain complex and interactive. They vary by age and sex of the child but also the sex of the parent. A concomitant study of adolescent and parent depression will provide data to analyze the prevalence of depressed parent adolescent depression and to define risk or protection factors.

AdoDesP study is a cluster randomised trial (randomisation of the GPs) which compare a group of adolescent with PC articulated with mental health service (MDA) and an other group without articulation (routine cares).

A third group of depressed adolescents will be constituted to analyse parental depression of depressed adolescents.

Condition Endogenous depression, Depression, Depression (Major/Severe), Depression (Adolescent), Depression (Pediatric), Depression (Adult and Geriatric), Depression (Treatment-Resistant), Depressed, depressive disorder, depressed mood, miserable, depressive disorders
Treatment MDA, MDA, Routine Cares, Parental depression
Clinical Study IdentifierNCT03811041
SponsorUniversity Hospital, Brest
Last Modified on3 February 2021


Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 11 yrs?
Gender: Male or Female
Do you have any of these conditions: Depression (Adolescent) or Depression (Treatment-Resistant) or Endogenous depression or Depression (Pediatric) or Depression (Adult and Geriatric) or ...?
Do you have any of these conditions: Depression (Adolescent) or Endogenous depression or Depression (Adult and Geriatric) or depressed mood or Depressed or Depression (Pediatric) or Depre...?
Do you have any of these conditions: miserable or Depressed or depressive disorders or Depression (Adult and Geriatric) or Depression (Treatment-Resistant) or depressed mood or Endogenous...?
Parents of groups 1 and 2
Major patient consulting his GP
Depressed patient
Parent of adolescent aged between 11 and 18 years old
Adolescents of groups 1 and 2
Aged more than 11 and less than 18 years old
Parent included in the study
Parents of group 3
Parent of depressed adolescent under care at the MDA of Marseille, included in the study and whose depression is confirmed by HSCL25 scale
Adolescents of group 3
Aged more than 11 and less than 18 years old
Depressed patient
Under care at the MDA of Marseille since less than 1 month

Exclusion Criteria

Parents of groups 1, 2 and 3
Minor patient
Enable to give his consent
Patient with guardianship or curatorship
Non consenting patient
Pregnant or nursing mother
Adolescents of groups 1 and 2
Aged < 11 or 18
Parent whose depression isn't confirmed by HSCL25 scale
Non consenting adolescent
Pregnant or nursing mother
Adolescent of group 3
Aged < 11 or 18
Non depressed adolescent
Non consenting patient
Pregnant or nursing mother
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