Platinum-Resistant Ovarian Cancer

Updated on 18 February 2020
platinum-resistant ovarian cancer


A Study of Tisotumab Vedotin for Patients With Platinum-Resistant Ovarian Cancer With a Safety Run-in of a Dose-Dense Regimen (innovaTV 208)

Women with platinum resistant ovarian cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.


Condition Ovarian Cancer
Clinical Study IdentifierTX217927
Last Modified on18 February 2020


Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Are you female?
Do you have Ovarian Cancer?
You may be eligible to participate in this study if you
Are a female at least 18 years of age or older
Have histologic documentation of epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer
You may not participate in this study if you
Have primary platinum-refractory disease, defined as disease progression within 2 months of completion of first line platinum-based therapy
Have had gastrointestinal obstruction within the past 6 months or who currently require parenteral nutrition
Have known past or current coagulation defects leading to an increased risk of bleeding
Have clinically significant cardiac disease
Have active ocular surface disease
Have ongoing, acute, or chronic inflammatory skin disease
Have uncontrolled tumor-related pain
Have Inflammatory lung disease requiring chronic medical therapy
Have Grade 3 or higher pulmonary disease unrelated to underlying malignancy
Have Grade >1 peripheral neuropathy
Have inflammatory bowel disease including Crohn’s disease and ulcerative colitis
Are pregnant, breastfeeding or plan to become pregnant
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How to participate?

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What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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