Neuromuscular Electrical Stimulation For The Treatment of Diabetic Peripheral Neuropathy (NMES for DPN)
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- STATUS
- Recruiting
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- End date
- Dec 31, 2023
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- participants needed
- 190
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- sponsor
- Imperial College London
Summary
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, affecting almost 50% of people with diabetes over the course of their lives. Symptoms vary from numbness to burning, aching and hypersensitivity in the lower limbs, indicative of sensory nerve loss. Motor neurons can also be affected, leading to muscle weakness and mobility issues, thus preventing patients from engaging in daily routines. Further sequelae include foot ulceration and Charcot's neuroarthropathy, which are risk factors for lower limb amputation and mortality. In the United Kingdom, the annual costs of DPN alone exceed £300 million, with further complications expected to cost an additional £1 billion. Currently, management strategies for DPN focus on prophylaxis and pain management. Neuromuscular electrical stimulation (NMES) is a novel nonpharmacological intervention for people with DPN. NMES is the application of electrical impulses which are of sufficiency intensity to improve artificial contraction of the muscle tissue and may help with DPN by improving microvascular blood flow and nerve conductivity by direct stimulation of the nerves.
Details
| Condition | Diabetic Peripheral Neuropathy, Diabetic Neuropathies, Diabetic Polyneuropathy, Diabetic Complication |
|---|---|
| Treatment | Revitive Medic (Actegy Ltd), Revitive Medic Coach (Actegy Ltd), Sham Revitive Medic Coach (Actegy Ltd) |
| Clinical Study Identifier | NCT03767478 |
| Sponsor | Imperial College London |
| Last Modified on | 23 March 2022 |
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