Last updated on December 2019

Anesthetics and Analgesics in Children


Brief description of study

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

Detailed Study Description

This is a research study to find out what the side effects are of certain drugs that are commonly used for pain and to put people to sleep for surgery. The researchers also want to know how the drug is broken down in the body. Participants will be given these drugs as they are prescribed by their regular doctor. As part of the participant's standard of care, doctors will perform tests, ask questions, review medical information and measure vital signs (heart rate, blood pressure, etc). The researchers will collect information that doctors have already written in the medical records. The research study team will collect blood from participants at certain time points depending on when the participant was first given the drug (up to 5 samples over the course of 10 to 48 hours). Parents will complete questionnaires about the study participant. Parents will continue to complete those same questionnaires for up to 12 months after the participant was first given the drug. Examples of current and upcoming anesthetics and analgesics include, but are not limited to: hydromorphone (Dilaudid), ketorolac (Toradol), methadone and ketamine.

Clinical Study Identifier: NCT03427736

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Baylor College of Medicine

Houston, TX United States
4.32miles
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University of Texas Health Science Center

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Saint Louis, MO United States
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Saint Louis, MO United States
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Albuquerque, NM United States
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Aurora, CO United States
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Charleston, SC United States
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Durham, NC United States
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Richmond, VA United States
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Toronto, ON Canada
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Wilmington, DE United States
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Hospital Sainte-Justine

Montreal, QC Canada
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Stanford, CA United States
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University of California San Francisco

San Francisco, CA United States
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Oregon Health and Science University

Portland, OR United States
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