The Role of VitD in Rehabilitation of Idiopathic Adolescent Scoliosis (ScoliVit)

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  • participants needed
  • sponsor
    University of Ioannina
Updated on 8 June 2022
vitamin d
Accepts healthy volunteers


The purpose of this current prospective study is to determine the role of vitamin D in the development and restoration of spinal deformities in adolescence.


The investigator will record the medical history of each patient and information such as age, body size (weight, height) and body mass index (BMI = kg / m ^ 2). Girls will also be given the time of appearance of menstruation, a factor that needs to be evaluated because the growth of the skeleton continues three years after its appearance. Patients will be subjected to Adam's Test, x-ray's and as well as lateral bending radiographs.In the first contact with each patient, will be evaluated bone density measured by DEXA as well as haematological testing including PTH, alkaline phosphatase (ALP), calcium (Ca), phosphorus( P ), Calcitonin and, of course, vitamin D (total and metabolite 25 (OH) D).

Each patient's follow-up will be completed in two years by a clinical examination every six months and a clinical, laboratory and radiological examination per year. Patients will be divided into two groups. In a group with patients with normal 25 (OH) D and in a second group with patients with low levels of 25 (OH) D. Members of the second group will receive substitution treatment with an appropriate formulation. The results will be collected and evaluated using statistical programme.

Condition Scoliosis; Adolescence
Treatment Alphacalcidol
Clinical Study IdentifierNCT03582917
SponsorUniversity of Ioannina
Last Modified on8 June 2022


Yes No Not Sure

Inclusion Criteria

Idiopathic Adolescent Scoliosis
Risser sign <3-4

Exclusion Criteria

Neuromuscular diseases
metabolic disease
Liver, lung, thyroid and parathyroid gland disorders
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