A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B

    Not Recruiting
  • participants needed
  • sponsor
    Assembly Biosciences
Updated on 4 August 2021
chronic hepatitis
hepatitis b e antigen


This three-part, Phase 1 protocol will be the first clinical study of ABI-H2158. Parts 1 and 2 will be a Phase 1a, dose-ranging assessment of ABI-H2158 in healthy adult volunteers. If the dose-related safety, tolerability, and pharmacokinetics (PK) of ABI-H2158 in healthy volunteers are deemed satisfactory, then the study will advance to Part 3, a Phase 1b, dose-ranging assessment of ABI-H2158 in non-cirrhotic, CHB patients.

Condition Hepatitis B, chronic hepatitis b
Treatment ABI-H2158, Placebo for ABI-H2158
Clinical Study IdentifierNCT03714152
SponsorAssembly Biosciences
Last Modified on4 August 2021

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