Genomic Investigation of Unusual Responders (GENIUS)
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- STATUS
- Recruiting
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- End date
- Nov 5, 2023
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- participants needed
- 100
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- sponsor
- University Health Network, Toronto
Summary
Studies have shown that tumors from the same patient may respond very differently to the same therapeutic agents. This study aims to investigate the genetic basis of tumors that respond abnormally well or poorly to therapeutic agents in an effort to understand the fundamental genetic basis of this response. The present protocol seeks to retrospectively perform Exome, next-generation (DNA) sequencing and/or other molecular techniques on tumor samples to identify the genetic basis of a patient's exceptional response to chemotherapy.
Details
| Condition | Cancer, Breast Cancer, Non-small Cell Lung Cancer, Colorectal Cancer, Genitourinary Cancer, Gynecological Cancer, Upper Aerodigestive Tract Cancer, Pancreatobiliary Gastrointestinal Cancer, Melanoma (Skin), Rare Cancer, Carcinoma of Unknown Primary |
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| Clinical Study Identifier | NCT03740503 |
| Sponsor | University Health Network, Toronto |
| Last Modified on | 5 May 2022 |
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