Long-acting G-CSF for Febrile Neutropenia

  • End date
    Nov 10, 2023
  • participants needed
  • sponsor
    Lei Li
Updated on 22 January 2021
granulocyte colony stimulating factor
colony stimulating factor
ovarian cancer
epithelial ovarian cancer


This study aims to analyze the effects of long-acting granulocyte colony stimulating factor (G-CSF) on the prevention febrile neutropenia (FN) in epithelial ovarian cancer. Patients are randomized into study group and control group. In study group, patients accept long-acting G-CSF 48 hours from the chemotherapy. While the control group accept regular treatment rather than long-acting G-CSF. The primary end is the incidence of FN in every course of chemotherapy. The secondary ends include: the incidences of myelosuppression, doses of G-CSF and its expenses, visits to outpatient and emergency clinics, adverse events related to G-CSF.

Condition Colony-Stimulating Factors, Cost Effectiveness, Ovarian Epithelial Cancer, Epithelial Ovarian Cancer, Febrile Neutropenia, Epithelial Ovarian Carcinoma, Adverse Event, Myelosuppression Adult, colony stimulating factor, colony stimulating factors, ovarian epithelial carcinoma, carcinoma of the ovary
Treatment long-acting granulocyte colony stimulating factor, Short-term granulocyte colony stimulating factor
Clinical Study IdentifierNCT03740464
SponsorLei Li
Last Modified on22 January 2021


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