Last updated on November 2018

Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Nasal polyp | Sinusitis | Aspirin Sensitivity | Asthma | Chronic
  • Age: Between 18 - 65 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Patient not responding to conservative treatment of 3 months of nasal steroid drops
  • Nasal polyp score 4/8
  • SNOT-22 30
  • Lund-Mackay CT score 14
  • One previous endoscopic sinus surgery or at least one peroral corticosteroid course or at least 3 courses of antibiotics within 2 years

Exclusion Criteria:

  • Age <18 years, age > 65 years
  • Complication of CRS (f.e. mucocele, invasive fungal rhinosinusitis)
  • Other diagnosis than CRSwNP (inverted papilloma, antrochoanal polyp etc.)
  • Previous external sinus surgery or Draf 3 procedure (or indication for external approaches or Draf 3
  • Bleeding diathesis
  • Pregnancy/ breastfeeding
  • Cystic fibrosis
  • Primary ciliary dyskinesia (PCD)
  • Sarcoidosis
  • Granulomatosis with polyangitis (GPA)
  • Eosinophilic granulomatosis with polyangitis (EGPA)
  • Immunosupression (diagnosed Spesific Antibody Deficiency (SAD), common variable immunodeficiency (CVI), HIV or use of biologicals/immunosuppressive medication)
  • Immunotherapy
  • Daily use of systemic corticosteroids
  • Communication problems (f.e. neurological/psychiatric disease, language skills)
  • Unlikely to comply
  • Other severe disease
  • Inability to be operated.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

Volunteer Sign-up

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.