Last updated on August 2019

Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Obesity | Overweight
  • Age: Between 45 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Male or female, age greater than or equal to 45 years at the time of signing informed consent
  • Body mass index (BMI) greater than or equal to 27 kg/m^2
  • Have established cardiovascular (CV) disease as evidenced by at least one of the following: prior myocardial infarction; prior stroke (ischemic or haemorrhagic stroke); or symptomatic peripheral arterial disease (PAD), as evidenced by intermittent claudication with ankle-brachial index (ABI) less than 0.85 (at rest), or peripheral arterial revascularization procedure, or amputation due to atherosclerotic disease

Exclusion Criteria:

  • Any of the following: myocardial infarction, stroke, hospitalisation for unstable angina pectoris or transient ischaemic attack within the past 60 days prior to the day of screening
  • HbA1c greater than or equal to 48 mmol/mol (6.5 %) as measured by the central laboratory at screening
  • History of type 1 or type 2 diabetes (history of gestational diabetes is allowed)

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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