Last updated on April 2019

A Study to Investigate the Safety and Efficacy of ABBV-105 Alone or in Combination With Upadacitinib (ABBV-599 Combination) in Participants With Active Rheumatoid Arthritis.


Brief description of study

This is a phase 2 study to evaluate safety and efficacy of ABBV-105 and ABBV-599 (ABBV-105 plus upadacitinib) vs placebo on a background of conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDS) for the treatment of signs and symptoms of Rheumatoid Arthritis (RA) at 12 weeks in biological disease-modifying anti-rheumatic drugs(bDMARD)-inadequate response (bDMARD-IR) or bDMARD-intolerant participants with moderately to severely active RA and to define optimal dose for further development.

Clinical Study Identifier: NCT03682705

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Valerius Medical Group /ID# 168123

Los Alamitos, CA United States
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Millennium Research /ID# 167453

Ormond Beach, FL United States
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BayCare Medical Group /ID# 170860

Saint Petersburg, FL United States
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FL Med Clinic, PA /ID# 206279

Zephyrhills, FL United States
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PRN of Kansas /ID# 167985

Wichita, KS United States
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June DO, PC /ID# 170670

Lansing, MI United States
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Dhmc /Id# 167476

Lebanon, NH United States
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Health Research Oklahoma /ID# 167370

Oklahoma City, OK United States
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Royal Victoria Infirmary, Newc /ID# 201976

Newcastle Upon Tyne, United Kingdom
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Ocean Rheumatology /ID# 170673

Toms River, NJ United States
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Recruitment Status: Open


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