Last updated on October 2018

Randomized Controlled Trial of Endovascular Therapy for Acute Large Vessel Occlusion With Large Ischemic Core


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Mechanical Thrombectomy | Large Ischemic Core
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Acute cerebral infarction
  2. Age 18
  3. NIHSS 6
  4. Prestroke Modified Rankin Score 0-1
  5. ICA or M1 Occlusion on CT angiography or MR angiography
  6. ASPECTS 3-5 or DWI-ASPECTS 3-5
  7. Endovascular treatment can be initiated within 4.5 hours from onset and within 60 minutes from randomization
  8. Patient or Legally Authorized Representative has signed the Informed Consent form

Exclusion Criteria:

  1. Significant mass effect with midline shift
  2. Known allergy to contrast agents
  3. Evidence of acute intracranial hemorrhage
  4. Female who is pregnant or suspicision of pregnant
  5. Clinical evidence of chronic occlusion
  6. High risk of hemorrhage (platelet < 40,000 /L, APTT > 50 second or PT-INR > 3.0)
  7. Participating in any other therapeutic investigational trial
  8. Subjects who, in the judgment of the investigator, are likely to be non-compliant or uncooperative during the study.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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