Last updated on January 2020

A Phase 3 Comparison of Platinum-Based Therapy With TSR-042 and Niraparib Versus Standard of Care Platinum-Based Therapy as First-Line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer


Brief description of study

This is a global, multicenter, randomized, double-blind, controlled Phase 3 study in patients with newly diagnosed, Stage III or IV non mucinous epithelial ovarian, fallopian tube, or peritoneal cancer (collectively referred to as "ovarian cancer"). The currently recommended standard of care therapy for the first line treatment of Stage III or IV ovarian cancer is the combination of paclitaxel and carboplatin, with or without concurrent and maintenance bevacizumab.

Clinical Study Identifier: NCT03602859

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Alaska Women's Cancer Care

Anchorage, AK United States
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Hartford Hospital

Hartford, CT United States
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Women's Cancer Care

Covington, LA United States
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Willis-Knighton Cancer Center

Shreveport, LA United States
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Holy Cross Hospital

Silver Spring, MD United States
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Baystate Medical Center

Springfield, MA United States
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UMass Memorial Medical School

Worcester, MA United States
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Billings Clinic

Billings, MT United States
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Holy Name Medical Center

Teaneck, NJ United States
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Mount Sinai Chelsea

New York, NY United States
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Stony Brook Cancer Center

Stony Brook, NY United States
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Aultman Hospital

Canton, OH United States
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Stephenson Cancer Center

Oklahoma City, OK United States
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Kaiser Permanente Northwest

Portland, OR United States
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Fox Chase Cancer Center

Philadelphia, PA United States
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UPMC Hillman Cancer Center

Pittsburgh, PA United States
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Avera Cancer Institute

Sioux Falls, SD United States
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Texas Oncology - Tyler

Tyler, TX United States
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Utah Cancer Specialists

Salt Lake City, UT United States
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Emily Couric Clinical Cancer Center

Charlottesville, VA United States
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Kadlec Regional Medical Center

Kennewick, WA United States
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Swedish Medical Center

Seattle, WA United States
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Rigshopitalet

Copenhagen, Denmark
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Institut Saint Catherine

Avignon Cedex 9, France
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Medisprof SRL

Cluj-Napoca, Romania
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SC Oncomed SRL

Timisoara, Romania
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Ochsner Clinic Foundation

New Orleans, LA United States
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Maine Medical Center

Scarborough, ME United States
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University of Maryland

Baltimore, MD United States
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Masonic Cancer Center

Minneapolis, MN United States
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Westchester Medical Center

Hawthorne, NY United States
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NYU Langone Medical Center

New York, NY United States
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West Penn Hospital

Pittsburgh, PA United States
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Lankenau Medical Center

Wynnewood, PA United States
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Rhode Island Hospital

Providence, RI United States
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Saint Thomas Medical Partners

Nashville, TN United States
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Houston Methodist Hospital

Houston, TX United States
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Centre Jean Perrin

Clermont-Ferrand, France
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Institut Claudius Regaud

Toulouse Cedex 9, France
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Queen Alexandra Hospital

Portsmouth, United Kingdom
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