Last updated on October 2018

Effects of IL-1 Receptor Antagonism on Testosterone Production in Women With Polycystic Ovary Syndrome

Brief description of study

A prospective, interventional, open-label, single-arm, proof-of-concept study: 32 women with Polycystic Ovary Syndrome (PCOS) will be treated with 100 mg of Anakinra/Kineret for 4 weeks. 1 week after last injection patients will have a follow-up and a dexamethasone visit after a dexamethasone suppression test. Goal of this study is to investigate the effect of the Interleukin 1( IL-1) receptor antagonist Anakinra/Kineret on laboratory and clinical features in women with PCOS.

Clinical Study Identifier: NCT03578497

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